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CAPROLACTAM

Chemical Identification
CAS #	105-60-2
Formula	C₆H₁₁NO
Synonyms	aminocaproic lactam; epsilon-caprolactam; hexahydro-2H-azepin-2-one; 2-oxohexamethyleneimine

Physical Properties
Physical description	Clear to milky white-colored solution with a mild, disagreeable odor.
Boiling point	515°F	Molecular weight	113.2
Freezing point/melting point	156°F	Vapor pressure	0.00000008 mmHg
Flash point	282°F	Vapor density	3.91
Specific gravity	1.02	Ionization potential
Lower explosive limit (LEL)	1.4%	Upper explosive limit (UEL)	8.0%
NFPA health rating		NFPA fire rating
NFPA reactivity rating		NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0523 (dust and particulate)	0524 (vapor)
Sampling group
Sampler/Sampling media	OSHA versatile sampler (OVS-7) - 13 mm XAD-7 tube (200/100 mg) with GFF enclosed [SKC 226-57]	OSHA versatile sampler (OVS-7) - 13 mm XAD-7 tube (200/100 mg) with GFF enclosed [SKC 226-57]
Sampling time^*	100 min	100 min
Sampling volume (TWA)^*	100 L	100 L
Sampling flow rate (TWA)^*	1 L/min	1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	HPLC-UV	HPLC-UV
Method reference	OSHA PV2012 (partially validated)	OSHA PV2012 (partially validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	1 mg/m³ (dust), 0.22 ppm (1 mg/m³) (vapor)	TLV-TWA	5 mg/m³ (inhalable fraction and vapor) [1997]	PEL-TWA	1 mg/m³ [dust], 5 ppm (20 mg/m³) [vapor]
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL	3 mg/m³ [dust], 10 ppm (40 mg/m³) [vapor]
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	N	Skin notation	N	Skin notation	N
Notes: Not established		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: IARC-4, TLV-A5		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Caprolactam

NIOSH: Pocket Guide to Chemical Hazards - Caprolactam

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Caprolactam. See annual publication for most recent information.
U.S. EPA Integrated Risk Information System: Caprolactam (CASRN 105-60-2).
EPA Air Toxics Website: Caprolactam. U.S. Environmental Protection Agency Technology Transfer Network.

Last Updated Date : 01/28/2021

SEC-BUTYL ACETATE†

Chemical Identification
CAS #	105-46-4
Formula	C₆H₁₂O₂
Synonyms	sec-butyl ester of acetic acid; 1-methylpropyl acetate

Physical Properties
Physical description	Colorless liquid with a pleasant, fruity odor.
Boiling point	234°F	Molecular weight	116.2
Freezing point/melting point	-100°F	Vapor pressure	10 mmHg
Flash point	62°F	Vapor density
Specific gravity	0.872	Ionization potential	9.91 eV
Lower explosive limit (LEL)	1.7%	Upper explosive limit (UEL)	9.8%
NFPA health rating	1	NFPA fire rating	3
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0441	0441
Sampling group	OVSG-1
Sampler/Sampling media	CSC tube (100/50 mg) [SKC 226-01]	SKC 575-002 Passive Sampler [SKC 575-002]
Sampling time^*	240 min	240 min TWA; 1 min STEL
Sampling volume (TWA)^*	12 L
Sampling flow rate (TWA)^*	0.05 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	OSHA 5000 (fully validated)	OSHA 1009 (fully validated)
Notes		To obtain sampling and analytical error similar to that available with active sampling, knowledge of the atmospheric pressure and temperature are required, and these should be obtained using NIST-traceable devices. If that is not possible, temperature is assumed to be 22.2 °C, and the atmospheric pressure is estimated based on the elevation of the sampling location. When estimates are used in place of traceable measurements the sampling and analytical error associated with passive sampling is substantially increased, and this makes it more difficult to demonstrate overexposures after considering the 95% lower confidence limit.
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA	200 ppm (950 mg/m³)	REL-TWA	200 ppm (950 mg/m³)	TLV-TWA		PEL-TWA	200 ppm (950 mg/m³)
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: See 29 CFR 1910.1000 Table Z-1.		Notes:		Notes: Visit the ACGIH TLV site for specific data		Notes:
Health factors: See NIH-NLM PubChem.		IDLH	1700 ppm
Carcinogenic classifications:		Notes: 10% of LEL
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - sec-Butyl acetate

NIOSH: Pocket Guide to Chemical Hazards - sec-Butyl acetate

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Butyl acetates, all isomers. See annual publication for most recent information.

Last Updated Date : 04/05/2024

Group Sampling Information
Sampling Media	Sampling Time (If there are exceptions they will be in Notes)	TWA Sampling Volume (If there are exceptions they will be in Notes)	TWA Flow Rate (If there are exceptions they will be in Notes)
CSC Tube (100/50 mg sections, 20/40 mesh), [SKC 226-01]	240 min	12 L	0.05 L/min

Analytes Sampling Information
Analytes	IMIS Code	Wipe Sampling
Isobutyl Acetate	1534	No
n-Butyl Acetate	0440	No
sec-Butyl Acetate	0441	No
tert-Butyl Acetate	0442	No
Toluene**	2460	No
Ethyl Benzene	1080	No
Perchloroethylene (Tetrachloroethylene)**	2020	No
Trichloroethylene**	2490	No
Xylene	2590	No
Trimethylbenzene	2505	No
Benzene***	0320	No
Ethyl Acetate****	1040	No
n-Propyl Acetate‡	2180	No
Pentane‡‡	1990	No
Cyclohexane‡‡‡	0810	No
Heptane*	1371	No
n-Hexane‡‡‡‡	1380	No
Nonane*	N807	No
Octane*	1957	No

Notes

Request any (up to three (3)) of these analytes together.

Alternatively request IMIS Code Q115 and SLTC will report any significant amounts of these analytes.

Results for unrequested analytes in this group will be reported if significant amount are found.

Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. Please indicate on the 91A which of these compounds are known to be present.

There is no need to contact SLTC before sampling.

*80 min (4L)

**Peak sampling 1 min (0.05 L) and Ceiling sampling 5 min (0.25 L)

***STEL sampling 15 min (0.75 L)

****120 min (6 L)

‡200 min (10 L)

‡‡45 min (2.25 L)

‡‡‡190 min (9.5 L)

‡‡‡‡98 min (4.9 L)

BORON TRIBROMIDE†

Chemical Identification
CAS #	10294-33-4
Formula	BBr₃
Synonyms	boron bromide; tribromoborane

Physical Properties
Physical description	Colorless, fuming liquid with a sharp, irritating odor.
Boiling point	194°F	Molecular weight	250.5
Freezing point/melting point	-51°F	Vapor pressure	40 mmHg at 57°F
Flash point		Vapor density
Specific gravity	2.64 at 68°F	Ionization potential	9.70 eV
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	3	NFPA fire rating	0
NFPA reactivity rating	2	NFPA special instruction	W: Reacts violently or explosively with water
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)
Sampling group
Sampler/Sampling media
Sampling time^*
Sampling volume (TWA)^*
Sampling flow rate (TWA)^*
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments
Method reference
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA		TLV-TWA		PEL-TWA
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C	1 ppm (10 mg/m³) [Construction and Maritime Industries only]	REL-C	1 ppm (10 mg/m³)	TLV-C	0.7 ppm [2015]	PEL-C	1 ppm (10 mg/m³)
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: The OSHA PEL applies to Construction and Maritime Industries only. See 29 CFR 1926.55 Table 1 and 29 CFR 1915.1000 Table Z-Shipyards.		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications:		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Boron tribromide

NIOSH: Pocket Guide to Chemical Hazards - Boron tribromide

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Boron tribromide. See annual publication for most recent information.

Last Updated Date : 06/01/2022

2-N-DIBUTYLAMINOETHANOL (DIBUTYLAMINOETHANOL)

Chemical Identification
CAS #	102-81-8
Formula	C₁₀H₂₃NO
Synonyms	dibutylaminoethanol; 2-dibutylaminoethanol; 2-di-N-butylaminoethanol; 2-di-N-butylaminoethyl alcohol; N,N-dibutylethanolamine

Physical Properties
Physical description	Colorless liquid with a faint, amine-like odor.
Boiling point	446°F	Molecular weight	173.34
Freezing point/melting point		Vapor pressure	0.1 mmHg
Flash point	195°F	Vapor density	6
Specific gravity	0.86	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	3	NFPA fire rating	2
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0866
Sampling group
Sampler/Sampling media	Silica gel tube (300/150 mg) [SKC 226-10-04]
Sampling time^*
Sampling volume (TWA)^*	24 L
Sampling flow rate (TWA)^*	0.2 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	OSHA modified NIOSH 2007 (fully validated)
Notes	Immediately after sampling, transfer each section of the tube to separate vials containing 2 mL desorbing solution [0.12 M HCl in 4:1 methanol:water]. OSHA personnel may obtain vials containing solution from SLTC.
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	2 ppm (14 mg/m³)	TLV-TWA	0.5 ppm [1980]	PEL-TWA	2 ppm (14 mg/m³)
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	Y	Skin notation	Y	Skin notation	Y
Notes: Not established		Notes:		Notes: BEI®		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: Not listed		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Dibutylaminoethanol

NIOSH: Pocket Guide to Chemical Hazards - 2-N-Dibutylaminoethanol

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 2-N-Dibutylaminoethanol. See annual publication for most recent information.

Last Updated Date : 12/15/2020

TRIETHANOLAMINE

Chemical Identification
CAS #	102-71-6
Formula	C₆H₁₅NO₃
Synonyms	tris(2-hydroxyethyl)amine; tri(hydroxyethyl)amine; trolamine; TEA (amino alcohol); nitrilo-2,2',2''-triethanol; triethylolamine; daltogen

Physical Properties
Physical description	Oily liquid with a mild ammonia odor.
Boiling point	635.7°F (decomposes)	Molecular weight	149.19
Freezing point/melting point	70.9°F	Vapor pressure	<0.01 mmHg
Flash point	365°F	Vapor density	5.14
Specific gravity	1.13	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	2	NFPA fire rating	1
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	T185
Sampling group
Sampler/Sampling media	GFF (37 mm), Type A/E [AP4003705]
Sampling time^*	100 min
Sampling volume (TWA)^*	100 L
Sampling flow rate (TWA)^*	1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	OSHA PV2141 (partially validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA		TLV-TWA	5 mg/m³ [1990]	PEL-TWA	5 mg/m³
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	NA	Skin notation	N	Skin notation	N
Notes: Not established		Notes: Not established		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: IARC-3		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Triethanolamine

NIOSH: Pocket Guide to Chemical Hazards - Triethanolamine

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Triethanolamine. See annual publication for most recent information.
NIOSH Registry of Toxic Effects of Chemical Substances (RTECS): KL9275000: Ethanol, 2,2',2"- nitrilotri-.
Blum, A. and Lischka, G.: Allergic contact dermatitis from mono-, di- and triethanolamine. Contact Dermatitis 36(3): 166, 1997.
National Toxicology Program: NTP toxicology and carcinogenesis studies of triethanolamine (Cas No. 102-71-6) in B6C3F1 mice (dermal studies). Nat. Toxicol. Program Tech. Rep. Ser. (518): 5-163, 2004.
Pohanish, R.P. (editor): Ethanolamines. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1028-1031.
Savonius, B, Keskinen, H., Tuppurainen, M. and Kanerva, L.: Occupational asthma caused by ethanolamines. Allergy 49(10): 877-881, 1994.
Stott, W.T., Radtke, B.J., Linscombe, V.A., Mar, M.-H. and Zeisel, S.H.: Evaluation of the potential of triethanolamine to alter hepatic choline levels in female B6C3F1 mice. Toxicol. Sci. 79(2): 242-247, 2004.
Stott, W.T., Waechter, J.M., Rick, D.L. and Mendrala, A.L.: Absorption, distribution, metabolism and excretion of intravenously and dermally administered triethanolamine in mice. Food Chem. Toxicol.38(11): 1043-1051, 2000.

Last Updated Date : 01/13/2021

DICYCLOPENTADIENYL IRON†

Chemical Identification
CAS #	102-54-5
Formula	C₁₀H₁₀Fe
Synonyms	bis(cyclopentadienyl) iron; ferrocene; iron dicyclopentadienyl

Physical Properties
Physical description	Orange, crystalline solid or orange-yellow powder with a camphor-like odor.
Boiling point	480°F	Molecular weight	186.1
Freezing point/melting point	343°F	Vapor pressure
Flash point		Vapor density
Specific gravity		Ionization potential	6.88 eV
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating		NFPA fire rating
NFPA reactivity rating		NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0904 (total); request using analyte code 9135	D100 (resp); request using analyte code 9130
Sampling group
Sampler/Sampling media	Tared low-ash 37 mm PVC filter, 5 microns [SLTC108]	Tared low-ash 37 mm PVC filter, 5 microns, preceded by 10 mm nylon Dorr-Oliver cyclone for respirable samples. [SLTC108]
Sampling time^*	240-480 min	240-480 min
Sampling volume (TWA)^*	960 L	816 L
Sampling flow rate (TWA)^*	2 L/min	1.7 L/min ±5%
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	Gravimetric	Gravimetric
Method reference	OSHA PV2121 (partially validated)	OSHA PV2121 (partially validated)
Notes	Samples are first analyzed gravimetrically. If the gravimetric result of a sample yields a concentration below the permissible exposure limit (PEL), the SLTC will report the calculated air concentration from the gravimetric result, qualified as less than or equal to the gravimetric result; no further work on the sample will be performed. If the gravimetric result indicates an air concentration greater than the PEL, the sample will proceed for elemental analysis. Results will be reported from the elemental analysis for the element only; the stated identity of the actual sample contents is based on the assumption that the material sampled is as identified by the compliance officer using available documentation of materials and processes. The stoichiometric factor for Ferrocene from iron is 3.331.	Samples are first analyzed gravimetrically. If the gravimetric result of a sample yields a concentration below the permissible exposure limit (PEL), the SLTC will report the calculated air concentration from the gravimetric result, qualified as less than or equal to the gravimetric result; no further work on the sample will be performed. If the gravimetric result indicates an air concentration greater than the PEL, the sample will proceed for elemental analysis. Results will be reported from the elemental analysis for the element only; the stated identity of the actual sample contents is based on the assumption that the material sampled is as identified by the compliance officer using available documentation of materials and processes. The stoichiometric factor for Ferrocene from iron is 3.331. The standard applies to the Respirable Fraction.
Special requirements	FOR TOTAL DUST SAMPLES, DO NOT USE A CYCLONE!!!	Samples must be collected with a Dorr-Oliver cyclone.

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA	15 mg/m³ (total dust), 5 mg/m³ (respirable fraction)	REL-TWA	10 mg/m³ (total dust), 5 mg/m³ (respirable)	TLV-TWA	10 mg/m³ [1990]	PEL-TWA	10 mg/m³ (total dust), 5 mg/m³ (respirable fraction)
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: See 29 CFR 1910.1000 Table Z-1.		Notes:		Notes:		Notes: See footnote [n].
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: Not listed		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Ferrocene

NIOSH: Pocket Guide to Chemical Hazards - Dicyclopentadienyl iron

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Dicyclopentadienyl iron, as Fe. See annual publication for most recent information.

Last Updated Date : 12/28/2020

COBALT CARBONYL (as Co)

Chemical Identification
CAS #	10210-68-1; 37264-96-3
Formula	C₈Co₂O₈
Synonyms	di-µ-carbonylhexacarbonyldicobalt; cobalt octacarbonyl; cobalt tetracarbonyl dimer; dicobalt carbonyl; dicobalt octacarbonyl; octacarbonyldicobalt

Physical Properties
Physical description	Orange to dark-brown, crystalline solid.
Boiling point	126°F (decomposes)	Molecular weight	341.94
Freezing point/melting point	124°F	Vapor pressure	0.07 mmHg
Flash point		Vapor density
Specific gravity	1.73 at 64.4°F	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating		NFPA fire rating
NFPA reactivity rating		NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)
Sampling group
Sampler/Sampling media
Sampling time^*
Sampling volume (TWA)^*
Sampling flow rate (TWA)^*
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments
Method reference
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	0.1 mg/m³	TLV-TWA	0.1 mg/m³ [1980]	PEL-TWA	0.1 mg/m³
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	N	Skin notation	N	Skin notation	NA
Notes: Not established		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: IARC-2B		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Cobalt carbonyl

NIOSH: Pocket Guide to Chemical Hazards - Cobalt carbonyl (as Co)

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Cobalt carbonyl [10210-68-1], as Co. See annual publication for most recent information.

Last Updated Date : 12/21/2020

PHENYL ETHER (VAPOR)†

Chemical Identification
CAS #	101-84-8
Formula	C₁₂H₁₀O
Synonyms	diphenyl ether; diphenyl oxide; phenoxy benzene; phenyl oxide

Physical Properties
Physical description	Colorless, crystalline solid or liquid (above 82°F) with a geranium-like odor.
Boiling point	498°F	Molecular weight	170.2
Freezing point/melting point	82°F	Vapor pressure	0.02 mmHg at 77°F
Flash point	239°F	Vapor density
Specific gravity	1.08	Ionization potential	8.09 eV
Lower explosive limit (LEL)	0.7%	Upper explosive limit (UEL)	1.5%
NFPA health rating	1	NFPA fire rating	1
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	2047
Sampling group
Sampler/Sampling media	XAD-7 tube (100/50 mg) [SKC 226-95]
Sampling time^*	100 min
Sampling volume (TWA)^*	20 L
Sampling flow rate (TWA)^*	0.2 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	OSHA PV2022 (partially validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA	1 ppm (7 mg/m³)	REL-TWA	1 ppm (7 mg/m³)	TLV-TWA	1 ppm [1979]	PEL-TWA	1 ppm (7 mg/m³)
PEL-STEL		REL-STEL		TLV-STEL	2 ppm [1979]	PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: This OSHA PEL is also applies to phenyl ether-biphenyl mixture vapors. See 29 CFR 1910.1000 Table Z-1.		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH	100 ppm
Carcinogenic classifications: Not listed		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Diphenyl oxide

NIOSH: Pocket Guide to Chemical Hazards - Phenyl ether (vapor)

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 2017.
Api, A.M. and Ford, R.A.: Evaluation of the dermal subchronic toxicity of diphenyl ether in the rat. Food Chem. Toxicol. 41(2): 259-264, 2003.
Hefner, R.E., Leong, B.K.J., Kociba, R.J. and Gehring, P.J.: Repeated inhalation toxicity of diphenyl oxide in experimental animals. Toxicol. Appl. Pharmacol. 33(1): 78-86, 1975.
Law, F.C. and Chakrabarti, S.: Irreversible binding of ¹⁴C-diphenyl ether-derived radioactivity to liver microsomes in vitro and tissue proteins in vivo. Drug Chem. Toxicol. 6(3): 285-294, 1983.
Law, F.C., Song, Y.Y. and Chakrabarti, S.: Disposition and metabolism of diphenyl ether in rats. Xenobiotics 13(10): 627-633, 1983.
Pohanish, R.P. (editor): Diphenyl oxide. Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 979-980.

Last Updated Date : 01/28/2021

METHYLENEDIANILINE (4-4'-METHYLENEDIANILINE; MDA)‡

Chemical Identification
CAS #	101-77-9
Formula	C₁₃H₁₄N₂
Synonyms	4,4'-diaminodiphenylmethane; para, para'-diaminodiphenyl-methane; dianilinomethane; 4,4'-diphenylmethanediamine

Physical Properties
Physical description	Pale-brown, crystalline solid with a faint, amine-like odor.
Boiling point	748°F	Molecular weight	198.3
Freezing point/melting point	198°F	Vapor pressure	0.0000002 mmHg at 77°F
Flash point	430°F	Vapor density	6.8
Specific gravity	1.15	Ionization potential	10.70 eV
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	2	NFPA fire rating	1
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	1732
Sampling group
Sampler/Sampling media	2 GFFs (37 mm) coated with sulfuric acid, in 3-piece cassette, separated by the ring section [SKC 225-9004]
Sampling time^*	100 min
Sampling volume (TWA)^*	100 L
Sampling flow rate (TWA)^*	1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-ECD
Method reference	OSHA 57 (fully validated)
Notes	Within 10 hours after sampling, transfer filters to glass vial containing 2 mL deionized water.
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media	Wipe with GFFs wetted with 0.6 mL of a 60/40 methanol/deionized water solution. Wipe samples are placed in a solution of 0.07 N H₂SO₄ for shipment. Solutions of 60/40 methanol/deionized water and 0.07 N H₂SO₄ are available from the SLTC for OSHA staff. Kits for on-site screening of aromatic amines are available from commercial suppliers. [AP4003705]
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA	10 ppb [5 ppb Action Level]	REL-TWA		TLV-TWA	0.1 ppm [1992]	PEL-TWA	0.01 ppm (0.08 mg/m³)
PEL-STEL	100 ppb	REL-STEL		TLV-STEL		PEL-STEL	0.1 ppm (0.8 mg/m³)
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	N	Skin notation	N	Skin notation	Y	Skin notation	Y
Notes: See 29 CFR 1910.1050, Methylenedianiline.		Notes: CARCINOGEN (Ca); REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 0.03 mg/m³). See Appendix A, NIOSH Potential Occupational Carcinogens.		Notes:		Notes: See also California Code of Regulations, Title 8 §1535. Methylenedianiline. (Construction) and §5200. Methylenedianiline. (General Industry)
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: IARC-2B, NIOSH-Ca, NTP-R, OSHA-Ca, TLV-A3		Notes: Ca
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - 4,4'-Diaminodiphenylmethane

NIOSH: Pocket Guide to Chemical Hazards - 4,4'-Methylenedianiline

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 4,4'-Methylene dianiline. See annual publication for most recent information.

Last Updated Date : 01/05/2021

METHYLENE BISPHENYL ISOCYANATE (MDI; 4,4-DIPHENYLMETHANE DIISOCYANATE)†

Chemical Identification
CAS #	101-68-8
Formula	C₁₅H₁₀N₂O₂
Synonyms	4,4-diphenylmethane diisocyanate; MDI; 4,4-diisocyanadiphenyl-methane; methylenebis(4-phenylisocyanate); methylene bis(phenyl isocyanate); methylene di-p-phenylene ester of isocyanic acid

Physical Properties
Physical description	White to light-yellow, odorless flakes.
Boiling point	597°F	Molecular weight	250.3
Freezing point/melting point	99°F	Vapor pressure	0.000005 mmHg at 77°F
Flash point	390°F	Vapor density
Specific gravity	1.23 (Solid at 77°F) 1.19 (Liquid at 122°F)	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	2	NFPA fire rating	1
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	1073
Sampling group
Sampler/Sampling media	Isocyanate Sampling Filter Kit - GFF (37 mm, open-faced) coated with 1 mg 1-(2-pyridyl)piperazine [SLTC103]
Sampling time^*	15 min
Sampling volume (TWA)^*	15 L
Sampling flow rate (TWA)^*	1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	UHPLC
Method reference	OSHA 5002 (fully validated)
Notes	Refrigerate coated filters and protect from light until used. Sample open-faced!!
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device	Hazard Assessment Test Kit for Aromatic Isocyanates
Model/Type	769-1002
Sampling information (see manufacturer instructions)	Isocyanate Surface and Dermal Sampling, Hazard Assessment Test Kit for Aromatic Isocyanates

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	0.005 ppm (0.05 mg/m³)	TLV-TWA	0.005 ppm [1985]	PEL-TWA	0.005 ppm (0.051 mg/m³)
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C	0.02 ppm (0.2 mg/m³)	REL-C	0.020 ppm (0.2 mg/m³) [10 minutes]	TLV-C		PEL-C
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: See 29 CFR 1910.1000 Table Z-1.		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH	75 mg/m³
Carcinogenic classifications: IARC-3, EPA-CBD;D		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3: --/5 mg/m³/55 mg/m³

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Diphenylmethane-4-4'-diisocyanate

NIOSH: Pocket Guide to Chemical Hazards - Methylene bisphenyl isocyanate

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Methylene Bisphenyl Isocyanate. See annual publication for most recent information.
NIOSH: Occupational Health Guideline for Methylene Bisphenyl Isocyanate. 1978.

Last Updated Date : 04/02/2025

CAPROLACTAM

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

SEC-BUTYL ACETATE†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

BORON TRIBROMIDE†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

2-N-DIBUTYLAMINOETHANOL (DIBUTYLAMINOETHANOL)

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

TRIETHANOLAMINE

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

DICYCLOPENTADIENYL IRON†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

COBALT CARBONYL (as Co)

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

PHENYL ETHER (VAPOR)†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

METHYLENEDIANILINE (4-4'-METHYLENEDIANILINE; MDA)‡

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References

METHYLENE BISPHENYL ISOCYANATE (MDI; 4,4-DIPHENYLMETHANE DIISOCYANATE)†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References