PYRETHRUM | Occupational Safety and Health Administration

PYRETHRUM†

Chemical Identification
CAS #	8003-34-7
Formula	No formula
Synonyms	Cinerin I or II; Jasmolin I or II; Pyrethrin I or II; Pyrethrins; pyrethrum I or II [Note: Pyrethrum is a variable mixture of Cinerin, Jasmolin, and pyrethrin.]

Physical Properties
Physical description	Brown, viscous oil or solid.
Boiling point	338°F (Pyrethrin I), 392°F (Pyrethrin II), 279°F (Cinerin I), 361°F (Cinerin II)	Molecular weight	328.4 (Pyrethrin I), 372.4 (Pyrethrin II), 316.4 (Cinerin I), 360.4 (Cinerin II)
Freezing point/melting point		Vapor pressure	Low
Flash point	180-190°F	Vapor density
Specific gravity	1 (approx)	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	2	NFPA fire rating	1
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	2216
Sampling group
Sampler/Sampling media	OSHA versatile sampler (OVS-2) - 13 mm XAD-2 tube (270/140 mg) with GFF enclosed [SKC 226-30-16]
Sampling time^*	60 min
Sampling volume (TWA)^*	60 L
Sampling flow rate (TWA)^*	1 L/min
Sampling volume (STEL/Peak/C)^*	15 L
Sampling flow rate (STEL/Peak/C)^*	1 L/min
Analytical method instruments	GC-ECD
Method reference	OSHA 70 (fully validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method	Limit the amount of bulk submitted to 1 g or 1 mL.

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA	5 mg/m³	REL-TWA	5 mg/m³	TLV-TWA	5 mg/m³ [1992]	PEL-TWA	5 mg/m³
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: See 29 CFR 1910.1000 Table Z-1.		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH	5000 mg/m³
Carcinogenic classifications: TLV-A4		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Pyrethrins, [liquid]

NIOSH: Pocket Guide to Chemical Hazards - Pyrethrum

Literature References

NOAA: CAMEO Chemicals - Pyrethrins, [solid].
ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Pyrethrum. See annual publication for most recent information.
Centers for Disease Control and Prevention: Pyrethroids pesticides. In Third National Report on Human Exposure to Environmental Chemicals, June 2005, DHHS/CDC. Atlanta: National Center for Environmental Health Division of Laboratory Sciences, NCEH Pub. No. 05-0570, pp. 405-415.
Bass, C., Schroeder, I., Turberg, A., Field, L.M. and Williamson, M.S.: Identification of mutations associated with pyrethroid resistance in the para-type sodium channel of the cat flea, Ctenocephalides felis. Insect Biochem. Mol. Biol. 34(12): 1305-1313, 2004.
Elflein, L., Berger-Preiss, E., Preiss, A., Elend, M., Levsen, K. and Wunsch, G.: Human biomonitoring of pyrethrum and pyrethroid insecticides used indoors: determination of the metabolites E-cis/trans-chrysanthemumdicarboxylic acid in human urine by gas chromatography-mass spectrometry with negative chemical ionization. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 795(2): 195-207, 2003.
Pohanish, R.P. (editor): Pyrethrins or Pyrethrum. In Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1986-1988.
Sonderlund, D.M., et al. Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessment. Toxicology 171(1): 3-59, 2002.

Last Updated Date : 01/11/2021

PYRETHRUM†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References